Humoral Immune Response to Keyhole Limpet Haemocyanin, the Protein Carrier in Cancer Vaccines
Figure 1
Experimental design of the study. (a) Protocol for immunization with KLH and for collection of blood samples. The asterisks indicate days of collecting blood samples. (b) Assaying KLH-specific circulating plasmablasts from the blood samples. The cells were assayed both from the total population of PBMC and from receptor-positive and -negative populations (a total of six separated populations for each volunteer) resulting from immunomagnetic sorting with respect to different HR.
