T Cell Reactivity against Mycolyl Transferase Antigen 85 of M. tuberculosis in HIV-TB Coinfected Subjects and in AIDS Patients Suffering from Tuberculosis and Nontuberculous Mycobacterial Infections

Table 2

IFN-𝛾 production of PBMC from tuberculin-positive and tuberculin-negative, HIV-negative and HIV-positive subjects.

	HIV negative		HIV positive (CDC-A)
Stimulus	tuberculin +	tuberculin –	tuberculin +	tuberculin –
	(7)	(6)	(17)	(11)
PPD	2417±662^∗,∘	157±56	852±369^∗∗	238±70
CF	1988±576^∗	86±28	1210±503^∗∗	176±63
Ag85	1644±672^∗	26±12	1141±456^∗∗	84±20
PHA	2635±845	2885±525	3281±1842	2637±1355

IFN-𝛾 production in day 7 culture supernatants from purified PBMC. Results are expressed as mean ± standard deviation (pg/mL).
*Significantly different from healthy tuberculin-negative/HIV-negative controls (𝑃<.05).
**Significantly different from healthy tuberculin-negative/HIV-positive controls (𝑃<.05).
°Significantly different from healthy tuberculin-positive/HIV-positive controls (𝑃<.05).