Clinical Study

Comparative Approach to Define Increased Regulatory T Cells in Different Cancer Subtypes by Combined Assessment of CD127 and FOXP3

Figure 1

CD127 mRNA expression in CD4+CD25high Treg cells and integration of CD127 in the analysis of human Treg cells. (a) Expression of CD127 mRNA in CD4+CD25high Treg cells and conventional CD4+CD25 T cells in healthy donors ( , control) and CLL patients ( , CLL) as determined by qPCR (*, , Student’s t-test). (b) Gating strategies for analysis of expression of CD127 in CD4+CD25highFOXP3+ Treg cells or (c) CD25 expression in CD4+CD127lowFOXP3+ Treg cells.
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