Research Article

Different Transcriptional Profiles of Human Monocyte-Derived Dendritic Cells Infected with Distinct Strains of Mycobacterium tuberculosis and Mycobacterium bovis Bacillus Calmette-Guérin

Figure 1

Flow cytometry analysis of phenotype markers on DCs infected with different mycobacterial strains. DCs, obtained from the same donor, were exposed to MTB H37Rv, MTB CMT97, BCG Aventis and BCG Japan for 3 h (MOI, 1) or left uninfected. Flow cytometric analysis of typical membrane molecule expression was performed 24 h after exposition to mycobacteria. Fluorescence histograms for each surface molecule (filled histograms) in comparison with isotype controls (empty histograms) are reported. Data are from a single donor, representative of 7, all with similar results.
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