Review Article

Exogenous Control of the Expression of Group I CD1 Molecules Competent for Presentation of Microbial Nonpeptide Antigens to Human T Lymphocytes

Table 1

miRNAs with putative binding sites in the 3′UTR of CD1A, CD1B, and CD1C genes.

GeneAlgorithm
miRandaaTarget Scanb

CD1A19a, 21, 28-5p, 31, 33a, 33b, 146a, 146b-5p, 214, 217, 361-5p, 383, 421, 448, 495, 590-3p, 590-5p, 708, 87321, 28-5p, 31, 33a, 33b, 125a-3p, 138, 146a, 146b-5p, 197, 205, 224, 421, 448, 495, 590-5p, 708

CD1B129-5p, 137, 185, 203, 224, 543129-5p, 137, 203, 543

CD1C26a, 26b, 33a, 124, 125a-5p, 125b, 129-5p, 181a, 181b, 181c, 181d, 190, 190b, 203, 216a, 216b, 218, 219-5p, 300, 326, 330-5p, 340, 367, 376a, 376b, 381, 410, 421, 433, 455-5p, 494, 495, 505, 506, 539, 543, 590-3p, 129722, 26a, 26b, 33a, 33b, 124, 125a-5p, 125b, 129-5p, 132, 185, 190b, 203, 212, 216a, 216b, 218, 219-5p, 221, 222, 300, 326, 330-5p, 376a, 376b, 410, 495, 425, 433, 455-5p, 489, 494, 505, 506, 539, 542-3p, 543, 590-5p, 599, 1297

aConserved miRNAs with good mirSVR scores [8].
bmiRNAs broadly conserved among vertebrates (bold) or conserved only among mammals.