Immune Dysregulation after Cardiothoracic Surgery and Incidental Thymectomy: Maintenance of Regulatory T Cells despite Impaired Thymopoiesis
Figure 5
Proportion of naïve CD4+ and Tregs. Proportion of CD4+ T cells and Tregs that are naïve (CD27+CD45RA+ or CD45RA+ for Treg) were examined by age group. In subjects with no surgery, proportion of CD4+ T cells and CD4+ Tregs that are naïve decrease between childhood and adulthood (; Mann-Whitney test). In subjects with low TREC median proportion of naïve cells is reduced compared with no Surgery at each age (), but there is no difference between children and adults ( for both; Mann-Whitney test).
