Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 versus TRIF in Progression to Chronic Disease

Figure 2

Survival differs between TLR3-deficient (TLR3−/−) and TRIF−/− mice with CVB3 myocarditis/DCM. (a) Survival of TLR3−/− mice compared to WT B6.129 controls (TLR3−/− versus WT, 𝑛=77/group). (b) Survival of TRIF−/− mice compared to WT BL/6 controls (TRIF−/− versus WT, 𝑛=45/group), ***:𝑃<0.001.

(a)

(b)