Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development

Table 1

Does CBIgE elevation predict allergy?

Parameters	Population studied, country	Reference
Parameters correlated with elevated CBIgE
Skin-prick test at age 4 yr	1456, England	[10]
Allergic sensitization and recurrent wheezing at age 7 yr	380 high-risk newborns, Canada	[13]
Allergic sensitization at 4 and 10 yr and asthma at 10 yr	1456, USA	[14]
Skin-prick test at age 5 yr, allergic rhinoconjunctivitis at age 20 yr, and total IgE  at ages 11 and 20 yr	200, Finland	[15]
High IgE and allergic sensitization between the ages of 18 and 24 months	1884, Sweden	[11]
Total IgE and allergic diseases before 5 years of age	1884, USA	[12]
Parameters not correlated with elevated CBIgE
No significant association with recurrent wheezing	1314, Germany	[16]
Not better than family history to predict infant atopy	2814, USA	[17]
Family history of atopy far more sensitive than CBIgE	1111, UK	[18]