Longitudinal Analysis of Tetanus- and Influenza-Specific IgG Antibodies in Myeloma Patients

Figure 3

Time-dependent impact of alloSCT on FLU- and TT-specific antibodies in selected patients. (a) Comparison of FLU and TT antibodies 6 months before and 6 months after alloSCT and autoSCT. For 21 alloSCT patients and for 14 autoSCT patients, samples had been collected for both of these time points. Differences were significant with 𝑃<0.001 for FLU-antibodies before and after alloSCT and with 𝑃<0.0001 for TT antibodies before and after alloSCT. No significant differences were found between FLU and TT antibody concentrations before and after autoSCT. (b) Comparison of FLU and TT antibodies collected less than 6 months after alloSCT and more than 6 months after alloSCT. Samples had been collected from 20 alloSCT patients at both time points. Differences in antibody titers were significant in the case of anti-FLU (𝑃<0.01) and anti-TT antibodies (𝑃<0.0001).

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