Table 2: Ido1 and the cell cycle genes expression in mouse breast tumor cells.

Fold changes in cell cycle genes expression
4T1/Ido1+ versus 4T1/Ido1− NT-5/Ido1− versus NT-5/Ido1+

G1 phase and G1/S transition

1CAMK2a1.35.4
2GPR1324.81.8s
3ITGB117.61.8
4PPP2r3a5.12.9
5PPP3ca4.22.1
6SKP23.81.5

S phase and DNA replication

7DNAJC27.71.5
8MKI678.82.3
9MRE11a4.91.2
10MSH23.31.5
11PCNA5.41.1
12RAD176.11.8
13RAD515.21.3

M phase

14BRCA27.11.8
15CCNA119.14.4
16CCNB110.96.8
17CDC25a3.11.9
18NEK24.41.1
19NPM21.73.1
20PRM110.01.6
21RAD213.32.8
22SMC1a8.61.4
23STAG15.83.0

G2 phase and G2/M transition

24CHEK131.21.3
25DNAJC27.71.5

Cell cycle checkpoint; cell cycle arrest

26BRCA27.11.8
27CDK5rap16.51.2
28CDKN1a(p21)11.62.0
29CDKN1b(p27)6.81.0
30CDKN2a(p16)9.92.4
31CASP35.61.4
32CHEK131.21.3
33DDIT31.814.3
34DST11.2 7.3
35HUS17.71.0
36INHA10.05.0
37MACF18.73.1
38NOTCH21.83.1
39PKD12.03.5
40PMP221.96.1
41SFN12.07.0

Regulation of the cell cycle

42ABL13.41.3
43ATM18.31.7
44BRCA112.51.3
45CCNC11.01.0
46PBL18.91.5
47E2F33.31.2
48TRP63(p63)27.36.8

4T1: stable clone with shRNA-negative control vector pGeneClip/Neomycin; 4T1/ Ido1−: stable clone with shRNA for IDO.
NT-5: stable clone with control vector pRc/CMV/Neomycin; NT-5/Ido1+: stable clone with cDNA IDO.
*A positive value (normal font) indicates fold of gene upregulation; a negative value (bold) indicates fold of gene downregulation. Genes which were found up/downregulated more than 3-fold at least in the one of the cell line are presented.