|
| Company Name | Product name | Phase of development* | HSV vaccine type | Mode of action† |
|
| Micro-Antigen Technologies, LLC | “Asymptomatic” Lipopeptide | PC | Peptide-based
Self-adjuvanting | P&T |
| AlphaVax, Inc. | HSV Vaccine ALPHAVAX | PC | Alphavirus vector | P&T |
| Genocea Biosciences | HSV2 Vaccine GENOCEA | PC | Undisclosed | P&T |
| Henderson Morley plc | L-particles | PC | VLP | P |
| Henderson Morley plc | PREPS (previral DNA replication enveloped particles) | PC | VLP | P |
| JN International Medical Corporation | Genital Herpes Vaccine JN INTERNATIONAL | PC | Subunit | P |
| Juvaris Biotherapeutics, Inc | JVRS100 with Herpes Simplex Virus-2 Antigens | PC | Subunit gB, gDt, gH/gL JVRS-100 adjuvant | P |
| Mymetics Corporation | Herpes Simplex Virus Vaccine MYMETICS | PC | VLP | P |
| Sanofi-aventis | ACAM529 | PC | Replication-defective virus | P&T |
| BioVex Inc. | ImmunoVEX HSV2 Vaccine | I | Live-attenuated virus | P |
| Pfizer Inc. | Genital Herpes DNA Vaccine PFIZER INC | I | DNA via PMED | T |
| AuRx, Inc. | Theraherb | III | Live-attenuated virus | T |
| GlaxoSmithKline plc | Simplirix | F | Subunit gD2
SBAS4 adjuvant | P |
| Acuvax Ltd (formerly Avantogen Limited) | HSV 2 ACUVAX | D | Live-attenuated virus
GPI-0100 adjuvant | T |
| Antigenics Inc. | AG702 | D | Subunit gB2
Human HSP-70 adjuvant | T |
| Antigenics Inc. | AG707 | D | Subunit 32 peptides
Human HSP-70 adjuvant | T |
| BioVex Inc. | ImmunoVEX HSV2/HPV Vaccine | D | HSV-2/HPV
Combined | P&T |
| Celldex Therapeutics, Inc. | Dl5-29 Vaccine CELLDEX | D | Live, replication-impaired virus | T |
| Celtic Pharma Management L.P. | DISC Pro | D | DISC | P |
| Novartis AG | Genital Herpes DNA Vaccine NOVARTIS | D | DNA | T |
| Celtic Pharma Management L.P. | TAHSV | F | DISC | T |
| Eli Lilly&Co. | Resiquimod ELI LILLY | F | TLR agonist | T |
| GenVec Inc. | Herpes Simplex Virus Type 2 Vaccine GENVEC | NA | Adenovirus vector | P&T |
| Profectus bioSciences, Inc. | Herpes Simplex Virus Vaccine PROFECTUS BIOSCIENCES | NA | DNA with recombinant VSV boost | T |
| Vical Inc. | Herpes Simplex Virus Type 2 Vaccine VICAL | NA | DNA
Vaxfectin adjuvant | T |
|
