Research Article
Family History of Autoimmune Disease in Patients with Aicardi-Goutières Syndrome
Table 1
History of autoimmune disease in parents of cases and controls.
| Characteristic | AGS cases | Control | OR | P value | 95% CI |
| Maternal history of AI (yes/no) | | | | | | No | 26 (83.9%) | 28 (90.3%) | 1.00 | | | Yes | 5 (16.1%) | 3 (9.7%) | 1.75 | 0.453 | 0.39–8.27 |
| Paternal history of AI (yes/no) | | | | | | No | 30 (96.8%) | 31 (100.0%) | 1.00 | | | Yes | 1 (3.2%) | 0 (0.0%) | — | | — |
| Maternal and/or paternal history of AI (yes/no) | | | | | | No | 25 (80.7%) | 28 (90.3%) | 1.00 | | | Yes | 6 (19.4%) | 3 (9.7%) | 2.24 | 0.288 | 0.51–9.91 |
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value from chi-squared test due to zero control subjects with a paternal history of AI.
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