The Impact of Osteopontin Gene Variations on Multiple Sclerosis Development and Progression

Table 2

Frequency distribution of OPN-156G/GG genotypes in MS patients and healthy controls.

Genotype SNP −156	^†MS (𝑛=728)	^†Controls (𝑛=912)
GG/GG	78 (10.7)	112 (12.3)
G/GG	304 (41.8)	384 (42.1)
GG	346 (47.5)	416 (45.6)
^‡OR = 0.91 𝑃=0.25 (95% CI: 0.79–1.06)

*Multiple sclerosis patients.
^†Number of subjects, proportions are shown in the brackets. Genotypic distribution did not deviate significantly from the Hardy-Weinberg equilibrium in any group (data not shown).
^‡Odds ratio (OR), 95% confidence limits (95% CI), 𝜒² test calculated on allelic frequencies, and 𝑃 values are 2-tailed.