The Impact of Osteopontin Gene Variations on Multiple Sclerosis Development and Progression

Table 4

Relapse rate in patients with bout onset displaying different OPN genotypes.

Outcome measure	Genotype
	AA; 𝑁=153	C; 𝑁=174	GG/GG; 𝑁=33	Non-GG; 𝑁=294	AAGG; 𝑁=26	CG; 𝑁=301
Relapse rate	0.5^a (0.2–1)	1.3 (0.6–1.7)	0.8 (0.4–1.2)	1.1 (0.5–1.3)	0.6 (0.2–1.3)	1.2 (0.5–1.5)
	𝑃=0.01^b		𝑃=0.09		𝑃=0.06

^aMedian values; interquartile ranges are shown in the brackets.
^bMann-Withney U test.