Dietary Supplementation with Omega-3-PUFA-Rich Fish Oil Reduces Signs of Food Allergy in Ovalbumin-Sensitized Mice
Figure 4
Dietary supplementation with n-3 PUFA decreases mucus production in small intestine of BALB/c-sensitized mice. BALB/c mice received 5% n-3 PUFA (control group) or 25% n-3 PUFA (N-3 PUFA group) as source of lipids in their diet 21 days before the sensitization. BALB/c mice were sensitized (allergic, OVA+) or not (nonallergic, OVA−) with OVA. Seven days after the booster, all mice received OVA diet. After 7 days, the mice were sacrificed and the intestine was taken for histology analyses. (a) Nonallergic control; (b) allergic control; (c) nonallergic n-3 PUFA; (d) allergic n-3 PUFA. Bar = 50 μm. In (e), data are reported as means ± SEM of mucus production for 5 mice in each group. * compared to nonallergic group (OVA−) with the same diet, and ** compared to allergic control group (ANOVA-Tukey).
