Research Article

Adaptive and Innate Immune Responsiveness to Borrelia burgdorferi sensu lato in Exposed Asymptomatic Children and Children with Previous Clinical Lyme Borreliosis

Figure 3

The Borrelia-induced secretion of IL-1β, IL-6, IL-10, and TNF in PBMC supernatants from Borrelia exposed asymptomatic children (filled circle), children with previous clinical LB (open square), and controls (filled triangle) as measured by Luminex. The Borrelia induced secretions are net values obtained after subtracting the level of spontaneous cytokine secretion from the level of outer surface protein-fraction (OF-) stimulated cytokine secretion. The median values are noted as lines in the figure. No statistically significant differences were found between groups.
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