BPI-ANCA and Long-Term Prognosis among 46 Adult CF Patients: A Prospective 10-Year Follow-Up Study
Table 2
PsA colonization, BPI-ANCA, and outcome. Adult CF-patients divided into groups based on Leeds classification and IgA BPI-ANCA levels at baseline and subsequent endpoints during followup.
Leeds classification
Leeds I + II
Leeds III
Leeds IV
BPI-ANCA level
BPI−
BPI+
BPI++
BPI−
BPI+
BPI++
BPI−
BPI+
BPI++
Inclusion ()
5
12
9
6**
1
1
6
5*
1
5 years % with endpoint
0
16.7%
33.3%
16.7%
0
0
0
20%
0
( with endpoint)
(2)
(3)
(1)
(1*)
10 years % with endpoint
0
33.3%
77.8%
33.3%
0
100%
0
20%
0
( with endpoint)
(4)
(7)
(2**)
(1)
(1*)
Last followup, % with endpoint
20%
41.7%
88.9%
33.3%
0
100%
0
40%
0
( with endpoint)
(1)
(5)
(8)
(2**)
(1)
(2*)
Patient with colon cancer.
**Patient with Burkholderia cepacia.