| Year | Age | Clinical symptoms | Laboratory tests | Therapy |
| 1983 | 33 | Arthralgias, fever | ANA+ Wasserman test+ | NSAIDs | 1985 | 35 | Exudative pleuritis pericarditis | | Prednisone bolus plus tapered doses | 1995 | 36 | Nephropathy proteinuria >10 g/day | ANA 1: 160, ds-DNA pos, LE phenomenon pos, CH50 620, proteinuria, hematuria | CY, prednisone bolus, AZA, auto-HSCT | 2000 | 50 | Asthenia, proteinuria 2 g/24 h | ANA 1: 320 homogeneous, ds-DNA neg, complement normal, proteinuria, hematuria | Mycophenolate mofetil 2 g/day, prednisone 1 mg/kg | 2005 | 55 | Tendinitis | ANA 1: 320 homogeneous, ds-DNA neg, LE phenomenon neg, complement normal, proteinuria 0.5 g/24 h | Mycophenolate mofetil 2 g/day, prednisone 2 mg/kg plus tapered doses | 2008 | 58 | Facial erythema | ANA 1: 320 homogeneous, ds-DNA neg, LE phenomenon neg, complement normal, proteinuria 0.5 g/24 h | Mycophenolate mofetil 2 g/day, prednisone 0.5 mg/kg, hydroxichloroquine | 2012 | 62 | Disease quiescent, the patient is well | ANA 1: 680 homogeneous, proteinuria 0.18 g/24 h, complement normal, ds-DNA neg | Mycophenolate mofetil 1 g/day, prednisone 0.5 mg/kg/every other day |
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