MASP-2 level changes in the survivors or nonsurvivors of septic shock. Plasma levels of MASP-2 were measured over the first 5 days in 16 patients after the diagnosis of septic shock. (a) MASP-2 profiles in the survivors: each line represents an individual patient; (b) MASP-2 profiles in the nonsurvivors; (c) comparison of the change of MASP-2 in survivors versus nonsurvivors at 6 hours after enrollment; (d) the association of changes in plasma levels of MASP-2 at 6 hrs after enrollment with hospital outcome. Kaplan-Meier survival analysis was performed to determine if patients with ≥10% increase of MASP-2 within 6 hours after the diagnosis of septic shock (solid line) had different in-hospital mortality rate compared with patients with ≥10% decrease of MASP-2 over the same time point (dashed line). *indicates statistical difference (P < 0.05).
