Maternal Plasma Phosphatidylcholine Fatty Acids and Atopy and Wheeze in the Offspring at Age of 6 Years
Table 7
Regression coefficients for the association between standardised values (-scores) of maternal plasma PC fatty acids and FEV1 at 6 years of age.
Change in FEV1 (L/s) per SD change of each fatty acid exposure variable
Maternal exposure
Unadjusted analysis
Adjusted* analysis
Beta
(95% CI)
Beta
(95% CI)
Total -3 PUFAs %
0.013
(−0.001, 0.028)
0.07
0.010
(−0.004, 0.024)
0.15
ALA %
−0.012
(−0.026, 0.003)
0.11
−0.009
(−0.024, 0.005)
0.18
DHA %
0.011
(−0.003, 0.026)
0.12
0.008
(−0.006, 0.022)
0.28
EPA %
0.016
(0.001, 0.030)
0.03
0.013
(−0.001, 0.027)
0.07
Total -6 PUFAs %
0.000
(−0.015, 0.014)
0.96
0.000
(−0.014, 0.014)
0.99
LA %
−0.004
(−0.019, 0.011)
0.59
−0.005
(−0.019, 0.009)
0.50
AA %
−0.001
(−0.016, 0.013)
0.84
0.000
(−0.014, 0.015)
0.99
Total -3 : -6 PUFAs ratio
0.013
(−0.001, 0.027)
0.08
0.010
(−0.004, 0.024)
0.16
ALA: unsaturated metabolic products
−0.016
(−0.031, −0.002)
0.03
−0.011
(−0.026, 0.003)
0.12
LA: unsaturated metabolic products
−0.007
(−0.022, 0.008)
0.36
−0.008
(−0.023, 0.006)
0.25
Unadjusted and adjusted analyses for each maternal variable are presented. RR: relative risk; ALA: alpha-linolenic acid; DHA: docosahexaenoic acid; EPA: eicosapentaenoic acid; LA: linoleic acid; AA: arachidonic acid. Beta derived from linear regression.
*Adjusted for parity and child’s sex and age.