Genetics of Myasthenia Gravis: A Case-Control Association Study in the Hellenic Population

Table 2

Genotype and allele distribution of IRF-5 variants in MG patients and controls. Statistical values calculated by 𝜒² test are also shown.

IRF-5 variants	Control	MG	𝑃value
rs60344245	𝑁=100 (%)*	𝑁=101 (%)
Genotypes
insertion/insertion	28 (28.0)	24 (23.8)
insertion/deletion	48 (48.0)	53 (52.4)	0.76
deletion/deletion	24 (24.0)	24 (23.8)
Alleles
insertion	104 (52.0)	101 (50.0)	0.76
deletion	96 (48.0)	101 (50.0)
rs10954213	𝑁=101 (%)	𝑁=84 (%)*
Genotypes
A/A	37 (36.7)	29 (34.5)
A/G	46 (45.5)	46 (54.8)	0.3
G/G	18 (17.8)	9 (10.7)
Alleles
A	120 (59.0)	104 (62.0)	0.7
G	82 (41.0)	64 (38.0)

*Analysis was not successful for a subset of samples.