TRAF1 Gene Polymorphism Correlates with the Titre of Gp210 Antibody in Patients with Primary Biliary Cirrhosis

Table 2

Distribution of TRAF polymorphisms (rs3761847 and rs2900180) in patients with primary biliary cirrhosis (PBC) and controls.

SNP	Allele/genotype	PBC (%) (𝑛=179)	Controls (%) (𝑛=300)	𝜒^2	𝑃 (Fisher exact)	OR
rs3761847	A/G	210/148	356/244	0.07	0.84	1.04 [0.79–1.35]
	AA	64 (35.8)	99 (33)	0.38	0.55	1.13 [0.77–1.67]
	AG	82 (45.8)	158 (52.7)	2.12	0.16	0.76 [0.52–1.10]
	GG	33 (18.4)	43 (14.3)	1.41	0.25	1.35 [0.82–2.22]
rs2900180	C/T	114/244	185/415	0.13	0.72	1.05 [0.79–1.39]
	CC	84 (46.9)	144(48)	0.052	0.85	0.96 [0.66–1.39]
	CT	76 (42.5)	127 (42.3)	0.001	>0.99	1.02 [0.70–1.49]
	TT	19 (10.6)	29 (9.7)	0.11	0.75	1.11 [0.60–2.04]