The Clinical Significance of the Dense Fine Speckled Immunofluorescence Pattern on HEp-2 Cells for the Diagnosis of Systemic Autoimmune Diseases

<table>Change in ANA test referral patterns. Historically, when the ANA HEp-2 test became available in the 1960s exclusively rheumatologist ordered the ANA test. With the emerging recognition that many other diseases are associated with ANAs, a broad range of clinical disciplines order the ANA test.</table>

Journal of Immunology Research

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Figure 2

Figure 2: The Clinical Significance of the Dense Fine Speckled Immunofluorescence Pattern on HEp-2 Cells for the Diagnosis of Systemic Autoimmune Diseases 

Figure 2 | The Clinical Significance of the Dense Fine Speckled Immunofluorescence Pattern on HEp-2 Cells for the Diagnosis of Systemic Autoimmune Diseases 