Review Article

Hamster and Murine Models of Severe Destructive Lyme Arthritis

Figure 2

Histopathological responses detected in irradiated ((a) and (b)) and nonirradiated ((c) and (d)) C3H/HeJ mice injected with B. burgdorferi sensu stricto isolate 297. Irradiated control mice (e) were injected with BSK medium. All specimens were acquired 21 days after challenge, with the exception of panel (c), day 14. Panels (a) and (b) were viewed with a 4x or 10x objective lens, respectively.
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(a)
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(b)
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(c)
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(d)
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(e)