Distinct Characteristics in Japanese Dermatitis Herpetiformis: A Review of All 91 Japanese Patients over the Last 35 Years
Table 2
Comparison of granular and fibrillar deposition groups.
Granular ()
Fibrillar ()
t-test
N or age/N of data available
N or age/N of data available
Gender
Male
(66.0%)
(66.7%)
Female
(34.0%)
(33.3%)
Age at the initial visit, mean ± SD (range), years
(1–86)
(16–78)
P = 0.436
Male
(1–86)
(16–78)
P = 0.071
Female
(18–72)
(22–68)
P = 0.780
Age at onset, mean ± SD (range), years
(1–73)
(12–74)
P = 0.295
Male
(1–73)
4
(12–74)
P = 0.114
Female
(14–72)
(29–50)
P = 0.630
Site of lesion
Elbow
(50.0%)
(16.7%)
Knee
(43.5%)
(16.7%)
Buttock
(54.3%)
(13.3%)
Elbow and/or knee and/or buttock
(65.2%)
(23.3%)
Face
(17.4%)
(10.0%)
Ear
(15.2%)
(6.7%)
Neck
(6.5%)
(16.7%)
Scalp
(10.9%)
(3.3%)
Groin
(8.7%)
(0.0%)
At least one predilection site
(78.3%)
(40.0%)
Extremities*
(43.5%)
(56.7%)
Trunk**
(58.7%)
(73.3%)
Whole body***
(6.5%)
(10.0%)
Other deposition in the papillary dermis
C3
(26.0%)
(12.1%)
IgG
(10.0%)
(12.1%)
IgM
(6.0%)
(3.0%)
Fibrinogen
(4.0%)
(0.0%)
Small bowel disease
(6.0%)
(3.0%)
Associated diseases
Diabetes mellitus
(10.0%)
(6.1%)
Lymphoma
(6.0%)
(0.0%)
Thyroid disease
(0.0%)
(3.0%)
Sjögren syndrome
(2.0%)
(0.0%)
HLA antigen§
DR4
(28.6%)#
(61.5%)##
DR9
(64.3%)¶
(23.1%)¶¶
*Not including cases limited only to elbow or knee; **not including cases limited only to buttock, neck, or groin; ***not including cases limited to combination of predilection sites; §frequency in HLA antigens of control was depicted from [90]. # (versus controls), (versus Fibrillar); ## (versus controls), ¶ (versus controls, corrected ), (versus Fibrillar), ¶¶ (versus controls).
