Immunogenicity and Protective Efficacy of a Novel Recombinant BCG Strain Overexpressing Antigens Ag85A and Ag85B
Figure 7
Representative lung pathology of C57BL/6 mice after challenge. Vaccinated C57BL/6 mice were challenged i.v. with 106 CFU virulent M. tuberculosis H37Rv strain. Four and 18 weeks after infection, lung tissue sections from different vaccine groups were prepared for HE staining (×40).
