Interactions of miR-34b/c and TP53 Polymorphisms on the Risk of Intracranial Aneurysm

Table 2

Genotype frequencies of miR-34 rs4938723 and TP-53 Arg72Pro between patients with intracranial aneurysm and controls.

Polymorphisms	Controls 𝑛=426 (%)	Patients 𝑛=164 (%)	OR (95% CI)	𝑃 value
rs4938723
TT	188 (44.1)	77 (47.0)	1.0 (ref)
CT	194 (45.6)	82 (50.0)	1.03 (0.71–1.49)	0.87
CC	44 (10.3)	5 (3.0)	0.28 (0.11–0.73)	0.006
TP-53
GG	145 (34.0)	60 (36.6)	1.0 (ref)
CG	223 (52.4)	77 (46.9)	0.83 (0.56–1.24)	0.37
CC	58 (13.6)	27 (16.5)	1.13 (0.65–1.94)	0.67

OR: odds ratio.
CI: confidence interval.
Ref: reference.