Interactions of miR-34b/c and TP53 Polymorphisms on the Risk of Intracranial Aneurysm

Table 3

The combined genotypes frequencies of miR-34 rs4938723 and TP-53 Arg72Pro between patients with intracranial aneurysm and controls.

Polymorphisms	Controls 𝑛 (%)	Patients 𝑛 (%)	OR (95% CI)	𝑃 value
rs4938723CT/TT + TP53CG/CC	255 (66.8)	100 (62.9)	1.0 (ref)
rs4938723CT/TT + TP53GG	127 (33.2)	59 (37.1)	1.19 (0.81–1.74)	0.39
rs4938723CT/TT + TP-53 CG/CC/GG	382 (89.7)	159 (97.0)	1.0 (ref)
rs4938723CC + TP-53 CG/CC/GG	44 (10.3)	5 (3.0)	0.27 (0.11–0.70)	0.004

OR: odds ratio.
CI: confidence interval.
Ref: reference.