Research Article

Systemic-Lupus-Erythematosus-Related Acute Pancreatitis: A Cohort from South China

Table 3

Comparison of demographic and clinical characteristics between SLE-related severe acute pancreatitis (SAP) and mild acute pancreatitis (MAP).

SAP MAP value

Demographic characteristics
 Female7 (87.50%)18 (94.74%)0.513
 Age of onset AP (y) 0.016
 Interval between onset of SLE and AP (m) 0.822
 Early AP ( 1 year)5 (62.50%)9 (47.37%)0.678
 SLEDAI score at onset of AP 0.44
 SLICC/ACR damage index 0.854
 Number of organs involved 0.893
 Intensive therapy of GC/ISA5 (62.50%)11 (57.89%)1
 Mortality6 (75%)4 (21.05%)0.014

Clinical characteristics
 Fever8 (100.00%)13 (68.42%)0.136
 Mucocutaneous involvement6 (75.00%)12 (63.16%)0.676
 Articular involvement3 (37.50%)10 (52.63%)0.678
 Serositis5 (62.50%)10 (52.63%)0.696
 Neuropsychiatric involvement2 (25.00%)5 (26.32%)1
 Renal involvement7 (87.50%)15 (78.95%)1.0

Laboratory findings
 Serum amylase* 0.077
 Serum lipase* 0.616
 Elevated serum transaminase7 (87.5%)11 (57.89%)0.201
 Thrombocytopenia8 (100%)10 (52.63%)0.026
 Leucopenia7 (87.50%)6 (31.58%)0.013
 Positive anti-dsDNA8 (100.00%)16 (84.21%)0.532
 Positive anti-Sm1/7 (14.29%)5/14 (35.71%)0.613
 Low C38/8 (100.00%)18/18 (100.00%)1
 Low C47/8 (87.50%)14/18 (77.78%)1
 Anti-Ro2/7 (28.57%)11/14 (78.57%)0.056
 Anti-La1/7 (14.29%)6/14 (42.86%)0.337

*Times in excess of the upper limit of normal (ULN).