Clinical Study

Restoration of Innate and Adaptive Immune Responses by HCV Viral Inhibition with an Induction Approach Using Natural Interferon-Beta in Chronic Hepatitis C

Figure 4

Effect of RBV plus PEG-IFN-alpha 2b using an “induction” approach with CPIT (NCT) on serum cytokines (a), (a′) and chemokines (b), (b′) in chronic hepatitis C patients with high viral load, genotype 1b (serotype I), and wild or intermediate types of ISDR (late virological responders). RBV: ribavirin, PEG-IFN: pegylated interferon, CPIT: cyclic and periodic interferon treatment, NCT: novel combination treatment. Significant difference: * 𝑃 < 0 . 0 5 , ** 𝑃 < 0 . 1 .
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