Evaluating Frequency, Diagnostic Quality, and Cost of Lyme Borreliosis Testing in Germany: A Retrospective Model Analysis

Table 2

Mean pass rates of proficiency testing participants in regard to samples tested and assay system used.

Sample	IHA		Polyvalent; EIA	IgG-; EIA	IgM-; EIA	IgG-; IFA		IgM-; IFA		IgG Blot	IgM blot	Line blot	IgG-; CLIA	IgM-; CLIA	Diagnostic Comment
Positive samples	Qual.	Quant.	Qual.	Qual.	Qual.	Qual.	Quant.	Qual.	Quant.	Qual.	Qual.	Qual.	Qual.	Qual.	Qual.
32/2006	100	88.9	95.5	97.0	90.7	93.5	93.5	64.3	61.5	97.1	95.1	97	95.7	11.5	98
62/2006	66.7	76.9	82	83.3	92.0	88.0	85.7	90.9	78.9	89.2	89	83.3	100	71.4	88.7
21/2007	93.3	82.4	90.9	96.1	95.7	79.3	80.8	100	100	93.9	89.4	94.1	96.8	100	51.7
62/2007	85.7	66.7	91.4	99.2	93.7	95.8	81.8	71.4	75	100	84.9	96.9	100	91.2	97.7
32/2008	78.6	78.6	96.3	97	91.4	95.7	81	80	75	88	88.5	96.2	100	100	71.0
61/2008	100	100	96.2	99.6	81.4	90.9	77.3	89.5	78.9	100	87.7	96.7	100	91.8	96.5
Mean	87.3	82.3	92.1	95.4	90.8	90.5	83.4	82.7	78.2	94.7	89.1	94.0	98.8	77.7	83.9
Negative samples	Qual.	Quant.	Qual.	Qual.	Qual.	Qual.	Quant.	Qual.	Quant.	Qual.	Qual.	Qual.	Qual.	Qual.	Qual.
31/2006	94.1	88.9	95.9	93.9	95.5	93.5	93.5	85.7	84.6	97.9	94.6	93.9	100	100	98.3
61/2006	100	100	99.6	100	93.4	92.0	90.5	95.5	94.7	96.1	95.6	100	100	96.4	99.4
22/2007	100	100	87.9	88.8	93.7	62.1	53.8	92.6	92	84.6	90.2	75	100	100	92.4
61/2007	69.2	71.4	11.8	53.5	94.1	41.7	40.9	95.2	95	77.7	96.9	87.9	100	91.2	87.4
31/2008	100	100	96.2	98.9	96.4	91.3	90.5	100	95	94.4	98.3	100	100	97.4	99.4
62/2008	100	100	96	96.8	97.1	86.4	81	100	94.4	93.8	98.2	91.7	100	93.9	98.1
Mean pass rates	93.8	93.3	81.2	88.6	95.0	77.8	75.0	94.8	92.6	90.7	95.6	91.4	100	96.5	95.8