Indolent B-Cell Lymphomas Associated with HCV Infection: Clinical and Virological Features and Role of Antiviral Therapy

Table 1

Clinical pathological studies describing indolent NHL subtypes associated with HCV infection.

	Year	Diagnosis	N^° pts	N^° pts tested for HCV	N HCV+ (%)	Genotypes	Cryoglobulinemia, 𝑁 (%)
Arcaini et al. [16]	2006	SMZL	309	255	49 (19)	1b (𝑛=10), 2b (𝑛=1), 2a/2c (𝑛=4)	13 (10)
Saadoun et al. [17]	2005	SLVL	18	18	18 (100)	1 (𝑛=7), 2 (𝑛=4),; 3 (𝑛=1), 4 (𝑛=1)	18 (100)
Arcaini et al. [18]	2007	NMZL	47	38	9 (24)	NA	2 (14)
Arcaini et al. [19]	2006	MALT-MZL; Skin; Salivary glands; Orbit; Other sites	172; 29; 32; 25; 66	172; 29; 32; 25; 66	60 (35%); 21 (43); 15 (47); 9 (36); 15 (22)	1a (𝑛=11), 1b (𝑛=1), 2a/2c (𝑛=10)	NA
Ferreri et al. [20]	2006	MALT-MZL orbit	55	55	7 (13)	NA	2 (29)
Paulli et al. [21]	2009	Subcutaneous MALT- MZL	13	13	13 (100)	2a/2c (𝑛=4), 2a (𝑛=2) 2b, (𝑛=1)	3 (75)
Tedeschi et al. [22]	2009	WM	140	140	21 (15)	NA	10 (48)
Arcaini et al. [23]	2011	WM; SMZL	122; 98	66; 92	6 (9); 25 (27)	NA; NA	0; 3
Goldaniga et al. [24]	2008	B-CLPD	156	113	6 (5)	NA	NA

SMZL: splenic marginal zone lymphoma; NMZL: nodal marginal zone lymphoma; SLVL: splenic lymphoma with villous lymphocytes; MZL: marginal zone lymphoma; FL: follicular lymphoma; LPL: lymphoplasmacytic lymphoma; MCL: mantle cell lymphoma; SLL: small lymphocytic lymphoma; NHL: non-Hodgkin’s lymphoma; B-CLPD: B-cell chronic lymphoproliferative disorders.