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Clinical and Developmental Immunology
Volume 2012 (2012), Article ID 640835, 8 pages
http://dx.doi.org/10.1155/2012/640835
Clinical Study

Ileal Inflammation May Trigger the Development of GP2-Specific Pancreatic Autoantibodies in Patients with Crohn’s Disease

1Division of Transplantation Immunology and Mucosal Biology, King’s College London School of Medicine at King’s College Hospital, London SE5 9RJ, UK
2Department of Gastroenterology and Clinical Nutrition, University College Hospital, 250 Euston Road, London NW1 2PG, UK
3Cellular Immunotherapy and Molecular Immunodiagnostics, Center for Research and Technology, Thessaly, 41222 Larissa, Greece
4Faculty of Natural Science, Lausitz University of Applied Sciences, 01968 Senftenberg, Germany
5GA Generic Assays GmbH, L.-Erhard-Ring 3, Dahlewitz, 15827 Berlin, Germany
6Department of Medicine, University of Thessaly Medical School, Viopolis, Larissa 41110, Greece
7Institute of Immunology, Technical University Dresden, Fetscherstrasse 74, 01307 Dresden, Germany

Received 22 June 2012; Accepted 7 September 2012

Academic Editor: Xavier Bossuyt

Copyright © 2012 Polychronis Pavlidis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Polychronis Pavlidis, Alastair Forbes, and Dimitrios P. Bogdanos, “Anti-GP2 antibodies in inflammatory bowel disease patients with ileal pouch,” Journal of Crohn's and Colitis, 2013. View at Publisher · View at Google Scholar
  • Christos Liaskos, Vassiliki Spyrou, Dirk Roggenbuck, Labrini V. Athanasiou, Timoklia Orfanidou, Athanasios Mavropoulos, Dirk Reinhold, Eirini I. Rigopoulou, Georgios S. Amiridis, Charalambos Billinis, and Dimitrios P. Bogdanos, “Crohn’s disease-specific pancreatic autoantibodies are specifically present in ruminants with paratuberculosis: Implications for the pathogenesis of the human disease,” Autoimmunity, pp. 1–7, 2013. View at Publisher · View at Google Scholar
  • Valentina Somma, Hani Ababneh, Ahmad Ababneh, Simona Gatti, Vittorio Romagnoli, Emanuele Bendia, Karsten Conrad, Dimitrios P. Bogdanos, Dirk Roggenbuck, and Gino Ciarrocchi, “The Novel Crohn's Disease Marker Anti-GP2 Antibody Is Associated with Ileocolonic Location of Disease,” Gastroenterology Research and Practice, vol. 2013, pp. 1–7, 2013. View at Publisher · View at Google Scholar
  • Christos Liaskos, Eirini I. Rigopoulou, Timoklia Orfanidou, Dimitrios P. Bogdanos, and Christos N. Papandreou, “CUZD1 and Anti-CUZD1 Antibodies as Markers of Cancer and Inflammatory Bowel Diseases,” Clinical and Developmental Immunology, vol. 2013, pp. 1–11, 2013. View at Publisher · View at Google Scholar
  • Maria Papp, and Peter L. Lakatos, “Serological studies in inflammatory bowel disease: how important are they?,” Current Opinion in Gastroenterology, vol. 30, no. 4, pp. 359–364, 2014. View at Publisher · View at Google Scholar
  • Marta Kovacs, Katalin Eszter Mueller, Maria Papp, Peter Laszlo Lakatos, and Mihaly Csoendes, “New serological markers in pediatric patients with inflammatory bowel disease,” World Journal of Gastroenterology, vol. 20, no. 17, pp. 4873–4882, 2014. View at Publisher · View at Google Scholar
  • Dirk Roggenbuck, Dirk Reinhold, Peter Schierack, Dimitrios P. Bogdanos, Karsten Conrad, and Martin W. Laass, “Crohn's disease specific pancreatic antibodies: clinical and pathophysiological challenges,” Clinical Chemistry and Laboratory Medicine, vol. 52, no. 4, pp. 483–494, 2014. View at Publisher · View at Google Scholar