Gene-Expression-Guided Selection of Candidate Loci and Molecular Phenotype Analyses Enhance Genetic Discovery in Systemic Lupus Erythematosus

Table 1

Summary of SNPs associated with autoantibody traits.

SNP	Chr.	Nearby Gene	Ancestry	Autoantibody	Odds ratio	𝑃 value
rs9521996 C	13	ANKRD10	AA	Anti-RNP	2.01	8.0 × 10^−4
rs1408806 G	9	TYRP1	EA	Anti-Sm	3.48	1.5 × 10^−3
rs4894215 G	2	—	EA	Anti-Ro	2.16	2.5 × 10^−3

SNP: single nucleotide polymorphism, chr.: chromosome, autoantibody: the antibody specificity associated with the particular SNP, odds ratio and 𝑃-value are calculated from the logistic regression model.