Gene-Expression-Guided Selection of Candidate Loci and Molecular Phenotype Analyses Enhance Genetic Discovery in Systemic Lupus Erythematosus

Table 3

Case control analysis of 11 SNPs tested in this study in each ancestral background.

SNP	African Americans			European Americans
	MAF	OR	𝑃 value	MAF	OR	𝑃-value
rs9521996 C	0.285	1.02	0.86	0.136	1.46	0.12
rs11199974 G	0.258	0.89	0.44	0.482	1.11	0.56
rs7785392 T	0.473	0.80	0.084	0.612	0.78	0.16
rs9568401 G	0.122	0.74	0.12	0.085	1.04	0.90
rs4892122 G	0.279	1.14	0.32	0.295	1.19	0.39
rs4778708 T	0.407	0.95	0.68	0.268	1.10	0.64
rs1340981 A	0.161	0.92	0.61	0.397	0.88	0.47
rs1408806 G	0.174	0.80	0.19	0.246	0.85	0.44
rs4894215 G	0.358	0.94	0.64	0.430	1.08	0.67
rs1569428 G	0.341	0.70	0.0070	0.430	0.92	0.68
rs1159916 C	0.405	0.74	0.018	0.333	0.88	0.49

SNP: single nucleotide polymorphism, MAF: minor allele frequency in controls, OR: odds ratio, as calculated from the logistic regression model.