- About this Journal ·
- Abstracting and Indexing ·
- Advance Access ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Articles in Press ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Clinical and Developmental Immunology
Volume 2012 (2012), Article ID 704063, 11 pages
Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants
1Department of Plastic Surgery, Chang Gung Memorial Hospital, Chang Gung University and Medical College, 199 Tun Hwa North Road, Taipei 105, Taiwan
2Department of Biological Science and Technology, National Pingtung University of Science and Technology 1 Hseuh-Fu Road, Neipu 91201, Pingtung, Taiwan
3Department of Hepatogastroenterology, Chang Gung Memorial Hospital, Chang Gung University and Medical College, 199 Tun Hwa North Road, Taipei 105, Taiwan
4Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University and Medical College, 199 Tun Hwa North Road, Taipei 105, Taiwan
5Department of Plastic Surgery, Chang Gung Memorial Hospital, Chia-Yi, Taiwan
Received 4 May 2012; Accepted 12 October 2012
Academic Editor: Gerald Brandacher
Copyright © 2012 Christopher Glenn Wallace et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- J. H. Barker, N. Stamos, A. Furr et al., “Research and events leading to facial transplantation,” Clinics in Plastic Surgery, vol. 34, no. 2, pp. 233–250, 2007.
- B. Devauchelle, L. Badet, B. Lengelé et al., “First human face allograft: early report,” The Lancet, vol. 368, no. 9531, pp. 203–209, 2006.
- J. M. Dubernard, E. Owen, G. Herzberg et al., “Human hand allograft: report on first 6 months,” The Lancet, vol. 353, no. 9161, pp. 1315–1320, 1999.
- J. M. Dubernard, P. Petruzzo, M. Lanze et al., “Functional results of the first human double-hand transplantation,” Annals of Surgery, vol. 238, no. 1, pp. 128–136, 2003.
- M. Strome, J. Stein, R. Esclamado et al., “Laryngeal transplantation and 40-moth follow-up,” New England Journal of Medicine, vol. 344, no. 22, pp. 1676–1679, 2001.
- J. M. Sacks, E. K. Horibe, and W. P. A. Lee, “Cellular therapies for prolongation of composite tissue allograft transplantation,” Clinics in Plastic Surgery, vol. 34, no. 2, pp. 291–301, 2007.
- M. Siemionow and G. Agaoglu, “Tissue transplantation in plastic surgery,” Clinics in Plastic Surgery, vol. 34, no. 2, pp. 251–269, 2007.
- T. Fehr and M. Sykes, “Tolerance induction in clinical transplantation,” Transplant Immunology, vol. 13, no. 2, pp. 117–130, 2004.
- S. J. Knechtle and W. J. Burlingham, “Metastable tolerance in nonhuman primates and humans,” Transplantation, vol. 77, no. 6, pp. 936–939, 2004.
- H. Waldmann, “Transplantation tolerance—where do we stand?” Nature Medicine, vol. 5, no. 11, pp. 1245–1248, 1999.
- A. M. C. Faria and H. L. Weiner, “Oral tolerance,” Immunological Reviews, vol. 206, pp. 232–259, 2005.
- Q. Meng, W. Wang, X. Shi, Y. Jin, and Y. Zhang, “Protection against autoimmune diabetes by silkworm-produced GFP-tagged CTB-insulin fusion protein.,” Clinical and Developmental Immunology, vol. 2011, Article ID 831704, 14 pages, 2011.
- G. Garcia, Y. Komagata, A. J. Slavin, R. Maron, and H. L. Weiner, “Suppression of collagen-induced arthritis by oral or nasal administration of type II collagen,” Journal of Autoimmunity, vol. 13, no. 3, pp. 315–324, 1999.
- A. L. Meyer, J. M. Benson, I. E. Gienapp, K. L. Cox, and C. C. Whitacre, “Suppression of murine chronic relapsing experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein,” Journal of Immunology, vol. 157, no. 9, pp. 4230–4238, 1996.
- J. G. Chai, E. James, H. Dewchand, E. Simpson, and D. Scott, “Transplantation tolerance induced by intranasal administration of HY peptides,” Blood, vol. 103, no. 10, pp. 3951–3959, 2004.
- N. Ishido, J. Matsuoka, T. Matsuno, K. Nakagawa, and N. Tanaka, “Induction of donor-specific hyporesponsiveness and prolongation of cardiac allograft survival by jejunal administration of donor splenocytes,” Transplantation, vol. 68, no. 9, pp. 1377–1382, 1999.
- N. Ishido, J. Matsuoka, T. Matsuno, K. Nakagawa, and N. Tanaka, “Induction of hyporesponsiveness and prolongation of cardiac allograft survival after jejunal administration of donor splenocytes and its abrogation by administration of gadolinium,” Transplantation Proceedings, vol. 30, no. 7, pp. 3881–3882, 1998.
- A. E. Ulusal, B. G. Ulusal, L. M. Hung, and F. C. Wei, “Heterotopic hindlimb allotransplantation in rats: an alternative model for immunological research in composite-tissue allotransplantation,” Microsurgery, vol. 25, no. 5, pp. 410–414, 2005.
- M. H. Sayegh, Z. J. Zhang, W. W. Hancock, C. A. Kwok, C. B. Carpenter, and H. L. Weiner, “Down-regulation of the immune response to histocompatibility antigens and prevention of sensitization by skin allografts by orally administered alloantigen,” Transplantation, vol. 53, no. 1, pp. 163–166, 1992.
- T. G. Mayer, A. K. Bhan, and H. J. Winn, “Immunohistochemical analyses of skin graft rejection in mice. Kinetics of lymphocyte infiltration in grafts of limited immunogenetic disparity,” Transplantation, vol. 46, no. 6, pp. 890–899, 1988.
- R. Büttemeyer, N. F. Jones, Z. Min, and U. Rao, “Rejection of the component tissues of limb allografts in rats immunosuppressed with FK-506 and cyclosporine,” Plastic and Reconstructive Surgery, vol. 97, no. 1, pp. 139–148, 1996.
- W. P. A. Lee, M. J. Yaremchuk, Y. C. Pan, M. A. Randolph, C. M. Tan, and A. J. Weiland, “Relative antigenicity of components of a vascularized limb allograft,” Plastic and Reconstructive Surgery, vol. 87, no. 3, pp. 401–411, 1991.
- H. L. Weiner, “Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells,” Microbes and Infection, vol. 3, no. 11, pp. 947–954, 2001.
- M. Battaglia, A. Stabilini, and M. G. Roncarolo, “Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells,” Blood, vol. 105, no. 12, pp. 4743–4748, 2005.
- M. Battaglia, A. Stabilini, B. Migliavacca, J. Horejs-Hoeck, T. Kaupper, and M. G. Roncarolo, “Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients,” Journal of Immunology, vol. 177, no. 12, pp. 8338–8347, 2006.
- J. J. A. Coenen, H. J. P. M. Koenen, E. Van Rijssen, L. B. Hilbrands, and I. Joosten, “Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells,” Blood, vol. 107, no. 3, pp. 1018–1023, 2006.
- D. S. Segundo, J. C. Ruiz, M. Izquierdo et al., “Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients,” Transplantation, vol. 82, no. 4, pp. 550–557, 2006.
- L. Strauss, T. L. Whiteside, A. Knights, C. Bergmann, A. Knuth, and A. Zippelius, “Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin,” Journal of Immunology, vol. 178, no. 1, pp. 320–329, 2007.
- R. Zeiser, V. H. Nguyen, A. Beilhack et al., “Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production,” Blood, vol. 108, no. 1, pp. 390–399, 2006.
- J. Mestecky and J. R. McGhee, “Immunoglobulin A (IgA): molecular and cellular interactions involved in IgA biosynthesis and immune response,” Advances in Immunology, vol. 40, pp. 153–245, 1987.
- J. Mestecky, Z. Moldoveanu, and C. O. Elson, “Immune response versus mucosal tolerance to mucosally administered antigens,” Vaccine, vol. 23, no. 15, pp. 1800–1803, 2005.
- M. H. Sayegh, S. J. Khoury, W. W. Hancock, H. L. Weiner, and C. B. Carpenter, “Induction of immunity and oral tolerance with polymorphic class II major histocompatibility complex allopeptides in the rat,” Proceedings of the National Academy of Sciences of the United States of America, vol. 89, no. 16, pp. 7762–7766, 1992.
- M. H. Sayegh, S. J. Khoury, W. W. Hancock, H. L. Weiner, and C. B. Carpenter, “Mechanisms of oral tolerance by MHC peptides,” Annals of the New York Academy of Sciences, vol. 778, pp. 338–345, 1996.
- W. W. Hancock, M. H. Sayegh, C. A. Kwok, H. L. Weiner, and C. B. Carpenter, “Oral, but not intravenous, alloantigen prevents accelerated allograft rejection by selective intragraft TH2 cell activation,” Transplantation, vol. 55, no. 5, pp. 1112–1118, 1993.
- S. Nisco, P. Vriens, G. Hoyt et al., “Induction of allograft tolerance in rats by an HLA class-I derived peptide and cyclosporine A,” Journal of Immunology, vol. 152, no. 8, pp. 3786–3792, 1994.
- R. I. Carr, J. Zhou, D. Ledingham et al., “Induction of transplantation tolerance by feeding or portal vein injection pretreatment of recipient with donor cells,” Annals of the New York Academy of Sciences, vol. 778, pp. 368–370, 1996.
- R. I. Carr, J. Zhou, J. A. Kearsey, A. W. Stadnyk, and T. D. G. Lee, “Prolongation of survival of primary renal allografts by feeding of donor spleen cells,” Transplantation, vol. 66, no. 8, pp. 976–982, 1998.
- J. Zhou, R. I. Carr, R. S. Liwski, A. W. Stadnyk, and T. D. G. Lee, “Oral exposure to alloantigen generates intragraft CD8+ regulatory cells,” Journal of Immunology, vol. 167, no. 1, pp. 107–113, 2001.
- Y. G. He, J. Mellon, and J. Y. Niederkorn, “The effect of oral immunization on corneal allograft survival,” Transplantation, vol. 61, no. 6, pp. 920–926, 1996.
- A. L. A. Dettino, A. J. S. Duarte, and M. N. Sato, “Induction of oral tolerance and the effect of interleukin-4 on murine skin allograft rejection,” Brazilian Journal of Medical and Biological Research, vol. 37, no. 3, pp. 435–440, 2004.
- X. Lu, L. Zhou, and S. Chen, “Prolongation of skin allograft survival by combined feeding of donor spleen cells and cyclosporine in mice,” Transplantation Proceedings, vol. 36, no. 8, pp. 2429–2431, 2004.
- D. Ma, J. Mellon, and J. Y. Niederkorn, “Oral immunisation as a strategy for enhancing corneal allograft survival,” British Journal of Ophthalmology, vol. 81, no. 9, pp. 778–784, 1997.
- D. Ma, J. Mellon, and J. Y. Nicderkorn, “Conditions affecting enhanced corneal allograft survival by oral immunization,” Investigative Ophthalmology and Visual Science, vol. 39, no. 10, pp. 1835–1846, 1998.
- J. Y. Niederkorn and E. Mayhew, “Phenotypic analysis of oral tolerance to alloantigens: evidence that the indirect pathway of antigen presentation is involved,” Transplantation, vol. 73, no. 9, pp. 1493–1500, 2002.
- K. R. Byrne and J. C. Fang, “Endoscopic placement of enteral feeding catheters,” Current Opinion in Gastroenterology, vol. 22, no. 5, pp. 546–550, 2006.