720768.fig.002a
720768.fig.002b
720768.fig.002c
720768.fig.002d
720768.fig.002e
720768.fig.002f
720768.fig.002g
720768.fig.002h
Figure 2: PMN or PMN-elastase induce dyshesion of tumor cells and loss of E-cadherin: pancreatic cancer cells (T3 M4; upper panel) and liver cancer cells (HuH7, lower panel) were seeded as monolayers (a and e), and then incubated with PMN (b and f), or PMN-elastase (c and g) for three hours (magnification ×400; d, h are zooms thereof). Dyshesion of cells was observed, and cells assumed a spindle shaped form (in d and h marked by an arrow).