Table 2: PMN and PMN-elastase cause dyshesion, loss of E-cadherin expression, and downmodulation of keratin in cancer cells.

T3M4HuH7
Cultivated withPMNPMN elastasePMNPMN elastase

Dyshesion*47,19% (±2,30)38,86% (±7,33)37,05% (±1,91)46,33% (±3,84)
E-cadherin expression**53,81 (±20,22)78,76% (±19,64)22,61% (±5,55)54,12% (±23,04)
Keratin expression36,78% (±20,13)31,85% (±20,18)17,57% (±9,56)37,20% (±28,77)

*Measured as area devoid of cells in relation (%) of the total cell area.
**Measured as mean fluorescence intensity (MFI) in relation to the MFI of untreated cells which were set as 100 %.