Table 2: European ancestry case-case analysis showing IRF5 haplotypes with associated functional elements and serological associations [64].

Tag SNP haplotypePromoter indelSplice variantExon 6 indelPoly-A variantSerologic association

(1) TACAInPresentInPresentAnti-Ro: OR = 1.50, P = 2.0 10−3  
Anti-dsDNA: OR = 1.51, = 7.4 10−3
(2) TATAInPresentDelPresentAnti-dsDNA: OR = 1.68, = 4.9 10−5
(3) TCTADelPresentInAbsentAnti-La: OR = 3.51, = 7.5 10−3
(4) GCTADelAbsentDelPresent
(5) GCTGDelAbsentInAbsent

The haplotypes are shown as each of the four alleles in order from 5′ to 3′ (rs2004640, rs3807306, rs10488631, rs2280714).
SNP: single nucleotide polymorphism, indel: insertion/deletion, Poly-A: poly-adenylation, In: insertion, Del: deletion, OR: odds ratio, P: P value.