Toll-Like Receptor Transcriptome in the HPV-Positive Cervical Cancer Microenvironment

Table 1

Sample size. Twenty-five frozen cervical biopsies were categorized into 3 groups; normal tissue, case IDs N1–N11; dysplastic tissue, case IDs D1–D10; invasive carcinoma tissue, case IDs C1–C4. Laser capture microdissection was used to separate each specimen into epithelium and stroma compartments. The HPV infection status is shown, and the specific HPV type is noted when known.

Case ID	Morphological diagnosis	HPV infection status	Case ID	Morphological diagnosis	HPV infection status
N1	Normal	Negative	D3	LSIL	Types 66, 82
N2	Normal	Negative	D4	LSIL	Types 6, 66
N3	Normal	Negative	D5	HSIL	Type 16
N4	Normal	Negative	D6	HSIL	Type 16
N5	Normal	Negative	D7	HSIL	Type 33
N6	Normal	Negative	D8	HSIL	Type 16
N7	Normal	Negative	D9	HSII	Type 16
N8	Normal	Negative	D10	HSII	TYPe 39
N9	Normal	Negative	C1	Carcinoma	Type 16
N10	Normal	Negative	C2	Carcinoma	HR HPV+
N11	Normal	Negative	C3	Carcinoma	HR HPV+
D1	LSIL	Type 31	C4	Carcinoma	HR HPV+
D2	LSIL	Type 51

LSIL: low-grade squamous intraepithelial lesion; HR: high risk; HSIL: high-grade squamous intraepithelial lesion.