827480.fig.003a
(a)
827480.fig.003b
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827480.fig.003c
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827480.fig.003d
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Figure 3: Increased Bcl-6 mRNA, IL-21 mRNA expression, and plasma IL-21 concentration in RA patients. (a) Detection of Bcl-6 mRNA expression in RA patients and healthy controls. Bcl-6 mRNA was estimated by real-time RT-PCR. Data correspond to the of 7 RA patients and 7 healthy controls (** ). (b) Detection of IL-21 mRNA expression in RA patients and healthy controls. IL-21 mRNA was estimated by real-time RT-PCR. Data correspond to the of 7 RA patients and 7 healthy controls (** ). (c) Plasma IL-21 concentration in RA patients ( ) and healthy controls ( ) (* ). (d) Relationship between plasma IL-21 concentration and the frequency of circulating Tfh cells in RA patients ( , ) ( ).