Emergence of Exhausted B Cells in Asymptomatic HIV-1-Infected Patients Naïve for HAART is Related to Reduced Immune Surveillance
Figure 3
IL-7 serum levels in asymptomatic HIV-1-infected patients and correlation with CD10−CD27− B cells frequency. (a) Comparative analysis of IL-7 serum levels (pg/mL) in HIV-1-uninfected donors and asymptomatic HIV-1-infected patients. ELISA was performed to measure the IL-7 concentration. (b) Correlation between IL-7 serum levels and percentage of CD10−CD27− B cells in asymptomatic HIV-1-infected patients. Differences between groups were evaluated using the two tailed Mann-Whitney test, and were considered significant at . Into the box plots, horizontal lines represent median values for each group, boxes show the 25th and 75th percentiles, and bars show SD. Association of 2 different data groups were analyzed by Spearman’s rank test. Each symbol represents one individual, and regression line is shown. N.C.= no correlation.
