Beneficial Effect of Bupleurum Polysaccharides on Autoimmune-Prone MRL-lpr Mice

Figure 7

Protein expression of IFN-γ, IL-6, MCP-1, MHC-II, F4/80, and C3 in the kidneys of MRL/lpr mice. (a) Renal expressions of IFN-γ, IL-6, MCP-1, MHC-II, F4/80, and C3 were examined by Western blot analysis. The presented blot was a representative of those obtained from three mices. GAPDH was used as loading control. (b) Results of quantitative analysis were expressed as means ± S.D. ratio of IFN-γ, IL-6, MCP-1, MHC-II, F4/80, and C3 to GADPH (𝑛=3). *𝑃<0.05, **𝑃<0.01, ***𝑃<0.001 compared with vehicle-treated model group, tested by ANOVA and Fisher’s PLSD.

(a)

(b)