Table 1: Patients’ clinical characteristics at baseline, month 3, and month 6.

Clinical characteristicsStatisticsValues ( ) at baselineValues ( )   at month 3Values ( )   at month 6

value 0.000*0.838
BPDAI (0–360)Mean  SD52.5 24.7#1.8 ± 4.51.5 ± 4.6
Median (min–max)50.0 (2.0–104.0)0.0 (0.0–15.5)0.0 (0.0–17.1)

value0.000*0.646
ABSIS (0–206)Mean ± SD44.7 ± 21.7#1.7 ± 4.11.4 ± 4.3
Median (min–max)43.5 (1.5–92.5)0.0 (0.0–14.1)0.0 (0.0–15.7)

value0.000*0.682
BPDAI pruritus index (0–30)Mean ± SD23.1 ± 7.30.5 ± 1.30.5 ± 1.7
Median (min–max)24.0 (0.0–30.0)0.0 (0.0–5.0)0.0 (0.0–7.0)

value0.000*0.001*
BP180 (U/mL)Mean ± SD87.9 ± 46.6#11.1 ± 12.18.7 ± 9.7
Median (min–max)88.4 (10.0–190.8)7.2 (2.3–49.1)6.6 (1.9–41.1)

value0.000*0.115
BP230 (U/mL)Mean ± SD36.5 ± 36.518.2 ± 12.915.7 ± 13.8
Median (min–max)26.4 (1.5–151.2)16.9 (1.4–56.2)9.0 (2.1–59.2)

*Wilcoxon’s signed rank test statistically significant; #variable normally distributed.