Research Article

Transfer of Maternal Immunity to Newborns of Diabetic Mothers

Table 3

Superoxide release by colostrum and blood mononuclear phagocytes (mean ± SD, 𝑁 = 1 0 in each treatment).

PhagocytesBacteriaSuperoxide release (nmol)
NormoglycemicHyperglycemicStatistical contrast

Colostrum
No1.9 ± 0.41.6 ± 0.1Phagocytes with bacteria versus without 𝐹 = 1 8 . 6 ; 𝑃 = 0 . 0 0 1
Yes2.1 ± 0.51.5 ± 0.2

Maternal bloodNo3.5 ± 1.1#4.9 ± 0.9#Colostrum versus blood 𝐹 = 1 0 .6; 𝑃 = 0 . 0 0 2
Yes4.4 ± 0.2*#6.1 ± 0.7+#

Cord bloodNo0.6 ± 0.2#3.8 ± 1.1+#Normo- versus hyperglycemic 𝐹 = 1 3 . 7 ; 𝑃 = 0 . 0 3
Yes1.2 ± 0.5*3.9 ± 0.9+#

Colostrum and blood mononuclear cells were preincubated or not with EPEC. Indicates differences between phagocytes incubated with bacteria and the control (without bacteria) within each group and sample; + indicates intergroup differences within each treatment (with or not bacteria) and sample; #indicates differences between sample (colostrum and blood) within each treatment (with or not bacteria) and group.