The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

Figure 1

Enumeration of circulating T_FH cells in whole blood. T_FH cells were counted in whole blood using four different phenotypic definitions. (a)–(d) Representative gating strategy. (e) CD4⁺/CXCR5⁺; (f) CD4⁺/CD45RO⁺/CXCR5⁺; (g) CD4⁺/CXCR5⁺/PD-1^hi; (h) CD4⁺/CXCR5⁺/ICOS^hi. No differences were detected between patients with RA and controls (𝑃≥0.4 in all cases). Spots represent individual patients. Mean ± SEM are shown.