Protection against SHIV-KB9 Infection by Combining rDNA and rFPV Vaccines Based on HIV Multiepitope and p24 Protein in Chinese Rhesus Macaques

<table>Schematic representation of the rDNA and rFPV vaccine constructs. The functional elements of the expression vector are the following. P<sub>CMV</sub>: human cytomegalovirus (CMV) immediate-early promoter/enhancer; Kozak: a Kozak translation-initiation sequence and an initiation codon (ATG) for proper initiation of translation; ER signal: endoplasmic reticulum signal peptide; MEG(4): multi-epitope gene (including 4 epitopes); P24: HIV-1 capsid protein; MEG(25): multi-epitope gene (including 25 epitopes); BGHpA: Bovine growth hormone (BGH) polyadenylation signal; TKL: the left recombinant fowlpox virus; P<sub>E/L</sub>: early and late promoter of fowlpox virus; T5NT: terminal signal of fowlpox virus; TKR: the right recombinant fowlpox virus.</table>

Journal of Immunology Research

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Figure 1

Figure 1: Protection against SHIV-KB9 Infection by Combining rDNA and rFPV Vaccines Based on HIV Multiepitope and p24 Protein in Chinese Rhesus Macaques 

Figure 1 | Protection against SHIV-KB9 Infection by Combining rDNA and rFPV Vaccines Based on HIV Multiepitope and p24 Protein in Chinese Rhesus Macaques 