Vaccination with Enzymatically Cleaved GPI-Anchored Proteins from Schistosoma mansoni Induces Protection against Challenge Infection
Figure 5
Liver pathology measured in mice vaccinated with GPI-anchored proteins. (a) Hepatic granuloma area, (b) Number of eggs per gram of hepatic tissue, (c) hepatic granuloma numbers, and (d) fibrosis area. The quantification of eggs and the number of granulomas in histological sections were performed using a microscope with 10x objective lens. The results are expressed in square micrometer for granuloma area, in eggs per gram of tissue for number of eggs, in granuloma per square milimeter for number of granuloma and fibrosis per square micrometer for granuloma fibrosis. A statistically significant difference of GPI vaccinated mice compared to control group is denoted by an asterisk for . Results are representative of two independent biological experiments.
