Review Article

Perinatal Programming of Childhood Asthma: Early Fetal Size, Growth Trajectory during Infancy, and Childhood Asthma Outcomes

Table 3

Summary of asthma and allergy outcomes in the context of changing growth trajectory during late pregnancy.

Second-third trimesterIncreased rate of growthReduced rate of growth
SymptomsAtopyLung functionSymptomsAtopyLung function

SouthamptonIncreased atopic wheezeIncreased skin prick positivity
Aberdeen 5 yearsIncreased asthma*
Aberdeen 10 yearsIncreased asthmaReduced FEV1 and FVC

*Data not published but can be confirmed by the author.