The Immune Factors Involved in the Pathogenesis, Diagnosis, and Treatment of Sjogren's Syndrome

Table 1

Prevalence and associated diseases of autoantibodies.

Antibodies	Prevalence (%)	Related autoimmune diseases
Rheumatoid factors (RF)	40–50	Hypergammaglobulinemia
Cryoglobulins	10–15	Lymphoma development and death
Anti-centromere antibodies (ACA)	4–17	Systemic sclerosis
Anti-mitochondrial antibodies (AMA)	5–6.5	Primary biliary cirrhosis
Anti-cyclic citrullinated peptide antibodies (anti-CCP)	7–10	Articular manifestations
Anti-smooth muscle antibodies (ASMA)	6.5–62	Autoimmune hepatitis